CAD, Stable Angina Pectoris
Conditions
Brief summary
The purpose of this study is to compare coronary angioplasty with stent implantation with an exercise rehabilitation program in patients with stable coronary artery disease (CAD).
Interventions
DEVICEPTCA and Stent Implantation
BEHAVIORALExercise Training
Sponsors
University of Leipzig
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Angiographically documented CAD, with at least one coronary artery stenosis of more than 50% in a native segment never subjected to intervention, which is recommended for treatment with percutaneous transluminal coronary angioplasty (PTCA). * Stable coronary artery disease * Eligible patients could be asymptomatic or have class I to III angina (Canadian Cardiovascular Society \[CCS\]) with documented myocardial ischemia * Angina pectoris threshold \> 50 Watt (cycle ergometry) * Permanent residence should be within 25 km of training facility.
Exclusion criteria
* \< 18 or \> 70 years of age * Patient currently participating in an exercise training program * Unstable angina pectoris or myocardial infarction during the last 2 weeks * Symptoms of CCS class IV * Exercise limitations due to clinical conditions not related to CAD * Left ventricular ejection fraction (LVEF) of \< 40% * Ventricular arrhythmia (Lown Ivb) * Hemodynamically significant valvular heart disease * Previous cardiac surgery * PTCA performed during the last 12 months * Any major non-cardiac condition that would adversely affect survival during the duration of the study * Reduced compliance
Countries
Germany
Contacts
Primary ContactRainer Hambrecht, Prof.
Outcome results
None listed