The Effect of Femoral Nerve Block on Postoperative Opioid Use After Anterior Cruciate Ligament (ACL) Reconstruction

Effect of Femoral Nerve Block on Opioid Requirements Following Anterior Cruciate Ligament Reconstruction: A Double Blind, Prospective Randomized Controlled Trial

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00175630

Enrollment

Registered

2005-09-15

Start date

2010-12-31

Completion date

2016-09-30

Last updated

2016-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Postoperative

Keywords

ACL reconstruction, morphine sparing, preemptive analgesia, Post-operative pain and post- operative opioid use

Brief summary

This study evaluates the effect of a femoral nerve block on opioid requirements following anterior cruciate ligament (ACL) reconstruction. This is a double blind, prospective randomized controlled trial.

Interventions

PROCEDUREAdministration of a femoral nerve block (bupivacaine HCL)

See Detailed Description

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

12 Years to 17 Years

Healthy volunteers

Inclusion criteria

* Schedule for primary elective anterior cruciate ligament reconstruction * Tolerance to bupivacaine * Tolerance to non-steroidal anti-inflammatory drugs (NSAIDs) * Informed consent

Exclusion criteria

* Patients who received a femoral nerve block more than 1 hour prior to surgery * Complex associated injuries or pre-existing conditions that will delay time to ambulation * Children with tibial avulsion fractures * Allergic and/or sensitive to bupivacaine and/or NSAIDs * 30% over ideal body weight * Acute ACL reconstruction (done less than 2 weeks after injury) * Pre-existing femoral nerve injury * Psychiatric patients on psychotropic agents * History of drug or alcohol dependence or recreational drug use * Refusal to provide informed consent

Design outcomes

Primary

Measure	Time frame
Postoperative morphine requirement	—

Secondary

Measure	Time frame
Pain rating	immediately post-op
Opioid surgical time	time from end of anaesthesia to first requirement of morphine

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026