Avascular Necrosis, Osteoarthritis
Conditions
Keywords
Osteoarthritis/Avascular Necrosis, Hip
Brief summary
This study evaluates femoral head resurfacing versus a large femoral head (Durom®) total hip system. This is a prospective randomized trial.
Interventions
PROCEDUREHip replacement
This study evaluates femoral head resurfacing versus a large femoral head (Durom®) total hip system. This is a prospective randomized trial.
Sponsors
University of British Columbia
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Indication for hip resurfacing because of osteoarthritis or avascular necrosis 2. Aged 19 to 65 years old 3. Ability to give informed consent
Exclusion criteria
1. Previous fracture requiring internal fixation of the hip 2. Previous hip osteotomy (pelvic or femoral) 3. Dysplasia requiring structural bone graft 4. Inability to respond to questionnaires in English (or French, Montreal centre only) 5. The presence of osteopenia or osteoporosis 6. Evidence of hepatic/renal insufficiency or failure from medical history or laboratory assessment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To estimate the difference in postoperative quality of life between patients with Durom® hip resurfacing versus those with total hip arthroplasty (THA) using a large-head, metal-on-metal articulation | at 2 years |
Secondary
| Measure | Time frame |
|---|---|
| To estimate the difference in concentrations of cobalt and chromium ions in serum | — |
| To estimate the difference in gait (pelvic tilt, forward velocity, and cadence) | at 12 and 52 weeks |
| To estimate the lower limb functional instability by a test of postural balance | — |
Countries
Canada
Outcome results
None listed