Images in Extracranial Artery Stenosis

The Differences in Images of Vertebral Artery Stenosis and Carotid Artery Stenosis Pre- and Post-Percutaneous Transluminal Angioplasty and the Gene Expression Patterns in Peripheral White Blood Cells

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00173927

Enrollment

100

Registered

2005-09-15

Start date

2004-03-31

Completion date

Unknown

Last updated

2007-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extracranial Atherosclerosis

Keywords

extracranial atherosclerosis, imaging, biomarkers

Brief summary

The goals of this trial are: 1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis. The positron emission tomography (PET)/MRI fusion imaging will be a promising tool to provide both anatomical and functional imaging for vulnerable plaques. 2. To identify patients at high risk of plaque rupture by image studies, biomedical profile, and gene expression of circulating monocytes.

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Patients with symptomatic extracranial atherosclerosis who are going to receive angiography and possible intervention.

Exclusion criteria

* Acute systemic illness * Creatinine \> 3 mg/dl * Unable to tolerate the tests (including MRI and PET/computed tomography \[CT\] scans)

Countries

Taiwan

Contacts

Primary ContactHsien-Li Kao, MD

hsienli_kao@yahoo.com886-2-2312-3456

Outcome results