Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00172302

Enrollment

Registered

2005-09-15

Start date

2005-11-30

Completion date

Unknown

Last updated

2005-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Failure, Chronic

Brief summary

Intravenous vitamin C may improve skin hyperpigmentation in chronic hemodialysis patients

Detailed description

Melanogenesis is caused by enzymatic conversion of tyrosine to melanin pigments.Ascorbic acid has the ability to inhibit peroxidase and may thus inhibit melanin synthesis.

Interventions

DRUGvitamin C, intravenous injection

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

* chronic hemodialysis patients

Exclusion criteria

* allergic to vitamin C, using steroid, etc

Design outcomes

Primary

Measure	Time frame
Skin pigmentation extent	—

Secondary

Measure	Time frame
blood anti-oxidant level	—

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026