Acute Viral Respiratory Infections in Elderly

Etiology and Impact of Acute Viral Respiratory Infections in Ambulatory Elderly Populations

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00170495

Enrollment

3000

Registered

2005-09-15

Start date

2004-09-30

Completion date

2006-07-31

Last updated

2010-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Infections, Acute

Keywords

respiratory illness, influenza, bronchitis, pneumonia, cold

Brief summary

This study is designed to assess the causes and impact of acute respiratory illness (common colds, flu, bronchitis, pneumonia) in adults age 65 and older. One of the ways to determine the virus causing a particular illness is to get a blood specimen when a person is sick and again later and look for the body's specific responses that identify the virus. Approximately 3000 subjects will be evaluated and their medical records assessed for details of recent illness and general health to help in understanding the subjects' current illness.

Detailed description

The purpose of this study is to determine the role of respiratory viruses in the etiology of medically attended acute respiratory illness in elderly populations and to assess the impact of these illnesses. Ambulatory elders presenting for health care with an acute respiratory illness will be recruited. Nose and throat swab specimens will be collected to test for one of the respiratory viruses, and acute and convalescent blood specimens will be collected to test for increases in specific antibody. Specimens will be collected within seven days of the onset of illness and then 1 month later for comparison specimens. A brief questionnaire will accompany the specimens, and more complete data on the illness and consequences will be obtained from the medical record. The pattern of illnesses by virus and their severity and duration will be determined.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

1. 65 years of age or older 2. Presentation to the geriatric clinic with an acute respiratory illness of less than 7 days' duration.

Exclusion criteria

1. Presentation to the geriatric clinic with a history of a respiratory illness of greater than 7 days' duration. 2. Physician/physician assistant judgment that the respiratory complaints do not represent an acute infection. 3. Patient declines to permit specimen collection.

Countries

United States

Outcome results