Pallidal Stimulation in Patients With Post-anoxic and Idiopathic Dystonia

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00169338

Enrollment

Registered

2005-09-15

Start date

2005-09-30

Completion date

2014-01-31

Last updated

2015-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dystonia

Keywords

Dystonia, deep brain stimulation, globus pallidus, Post-anoxic dystonia

Brief summary

Bilateral pallidal stimulation is effective in the treatment of patients with generalised idiopathic dystonia. The aim of this study is to evaluate the efficacy of bilateral pallidal stimulation in patients with post-anoxic generalised dystonia or non-generalised primary dystonia.

Detailed description

Evaluate the effect of bilateral pallidal stimulation on the motor disability of patients with post-anoxic generalised dystonia or primary dystonia.

Interventions

PROCEDUREDeep brain stimulation

internal pallidal deep brain stimulation

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

15 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Post-anoxic generalised dystonia * Idiopathic non-generalised dystonia * Disease duration \> 1 year

Exclusion criteria

* Contraindication to magnetic resonance imaging (MRI) * Mini-mental status (MMS) \< 24 * Severe psychiatric disorder

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026