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Contraception in Normal and Subnormal Men

Hormonal Male Contraception in Men With Normal and Subnormal Semen Parameters

Status
Terminated
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00167141
Enrollment
41
Registered
2005-09-14
Start date
2005-02-28
Completion date
2008-01-31
Last updated
2010-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

male fertility, semen parameters

Brief summary

Volunteers with normal and subnormal semen parameters receive a hormonal male contraceptive in order to investigate whether there are differences between normal and subnormal men in terms of suppressibility, rate of azoospermia and reversibility of suppression of spermatogenesis.

Detailed description

Volunteers with normal and subnormal semen parameters receive a hormonal male contraceptive in order to investigate whether there are differences between normal and subnormal men in terms of suppressibility, rate of azoospermia and reversibility of suppression of spermatogenesis. Twenty-five men will be recruited for each group. They will be exposed to hormonal male contraception for six months.

Interventions

DRUGinjection of hormonal male contraceptive

testosterone injections 4 times

Sponsors

University Hospital Muenster
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
20 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Volunteers with normal and subnormal semen parameters

Design outcomes

Primary

MeasureTime frame
semen parameters2005 - 2008

Secondary

MeasureTime frame
hormones2005 2008

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026