RCT to Investigate Whether an Exercise Programme Improves the Physical Performance and QOL After BMT

Randomised Controlled Trial to Investigate the Effects of an Exercise Programme on Physical Performance and Quality of Life After a Bone Marrow Transplant

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00163644

Enrollment

Registered

2005-09-14

Start date

2003-11-30

Completion date

Unknown

Last updated

2016-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematological Malignancies

Keywords

Hematological malignancies., Bone- marrow/ haemopoetic transplant, Exercise

Brief summary

The hypothesis is that exercise will improve the physical performance and quality of life of bone marrow/ haemopoietic stem cell transplants.The aim of the trial is to provide definite clinical evidence as to which( if any) type of exercise is most beneficial for this patient population. It is also aimed at improving the provision of physiotherapy services to this group of patients.

Detailed description

A three group, single blinded, randomised trial was designed to compare the effects of 1. aerobic plus active exercise and 2. aerobic plus resistance exercise to 3. control group of bone marrow/haemopoietic recipients not recieving exercise. The hypotheses being tested is that 1. Exercise improves the physical performance of transplants recipients. 2. Exercise improves the quality of life of these patients; 3. resisted exercise added to aerobic exercise increases muscle strength or lean muscle mass and 4. There are no adverse events during either form of exercise

Interventions

PROCEDUREaereobic plus resisted exercise

PROCEDUREaerobic plus active exercise

OTHERNo formal exercise plus phone calls

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Recipient bone marrow transplant Alfred Hospital, Platelets \>= 20 x 10E9 / l Provide written consent, 30 days after a bone marrow transplant have an absolute neutrophil count of 1x10E9/l be in a stable medical condition

Exclusion criteria

febrile neutropenia Have active graft versus host disease Have cardiomyopathy (ejection fraction \< 20%) require \> 28% oxygen

Design outcomes

Primary

Measure	Time frame
Physical performance.	At 6 weeks
Quality of Life.	At 6 weeks
Anthropometry and Grip strength	At 6 weeks

Secondary

Measure	Time frame
Heart Rate.	At 6 weeks
No adverse events during treatment.	At 6 weeks

Countries

Australia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026