Schizophrenic Disorders
Conditions
Keywords
schizophrenia, first episode, cognitive behavioural therapy, psychoeducation
Brief summary
The study is a randomized clinical trial investigating the efficacy of a comprehensive psychological intervention for the treatment of first episode schizophrenia
Detailed description
Patients suffering from their first episode of schizophrenic disorders are randomly allocated to either a short information centered psychoeducation (ICP) of 8 sessions or a cognitive behavioral treatment (CBT). CBT includes 8 sessions of psychoeducation, 8 sessions of computer based cognitive training, 8 sessions with relatives and 20 sessions of focusing on stress management, relapse prevention and coping with persistent symptoms. The primary endpoint is relapse at the one and two year follow up.
Interventions
BEHAVIORALcognitive behavioural therapy
BEHAVIORALpsychoeducation
Sponsors
University Hospital Tuebingen
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* diagnosis of schizophrenic disorder according to ICD 10: F20 * first episode * age between 18 and 55 * willingness to give informed consent also to a double blind pharmacological treatment study
Exclusion criteria
* residence outside of the catchment area * insufficient knowledge of the German language * substance abuse or addiction as primary clinical problem * serious physical illness * organic brain disease * pregnancy * contraindications to neuroleptic treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| relapse | — |
Secondary
| Measure | Time frame |
|---|---|
| quantitative measures of symptoms | — |
| social functioning | — |
| cognitive functioning | — |
| quality of life | — |
Countries
Germany
Outcome results
None listed