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Endorectal Coil Magnetic Resonance Images (ERC-MRI)

Development of a Prostate Deformation Model to Enable Accurate Registration of Endorectal Coil Magnetic Resonance Images (ERC-MRI) to Reference Treatment Planning CT Images

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00160953
Enrollment
20
Registered
2005-09-12
Start date
2005-02-28
Completion date
2010-02-28
Last updated
2010-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostatic Neoplasms

Brief summary

When we acquired MR images of the prostate gland using a coil (receiver antenna) inside the rectum, we can see areas with tumour in the prostate gland, and well as details of the anatomy. The coil inside the rectum changes the shape of the prostate gland. In order to use this images to help target radiation therapy to the tumour better, we need to deform the images to the original shape of the prostate gland without the coil. In this study, we will develop a way to deform the images accurately.

Interventions

PROCEDUREEndorectal Coil Magnetic Resonance Images

Sponsors

Abbott
CollaboratorINDUSTRY
Canadian Association of Radiation Oncology
CollaboratorINDUSTRY
Uro-Oncologic Radiation Award
CollaboratorUNKNOWN
University Health Network, Toronto
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* adenocarcinoma of the prostate * patient undergoing dose escalated conformal EBRT * low or intermediate risk prognostic factors: PSA \< or equa to20, gleason score \<8, T \<T3, N category 0 or X, M category 0 or X * \> or equal to 18 years of age * ECOG performance status 0 or 1

Exclusion criteria

* contraindications to MRI * bleeding diathesis and anti-coagulative therapy that cannot be temporarily ceased precluding insertion of fiducial markers * IFB or collagen vascular disease * previous colorectal surgery * previous pelvic RT

Design outcomes

Primary

MeasureTime frame
The primary aim of this study is to develop a prostate deformation model using the finite element method from anatomic MR images of the prostate gland acquired with and without ERC.—

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026