POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis)

A Monocenter, Double-blind, Randomized Trial, With Two Parallel Groups Comparing the Clinical Efficacy of Levocetirizine 5 mg Capsules and Desloratadine 5 mg Capsules Taken Once a Day Over 3 Weeks of Treatment in Adult Subjects Suffering From Seasonal Allergic Rhinitis (SAR) Due to Grass Pollen

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00160537

Enrollment

200

Registered

2005-09-12

Start date

2005-05-31

Completion date

2005-07-31

Last updated

2013-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seasonal Allergic Rhinitis

Keywords

Seasonal Allergic Rhinitis (SAR), Grass pollen, SAR Symptoms (sneezing, rhinorrhea, nasal / ocular pruritus, nasal congestion), POPULAR, Xyzal, Levocetirizine

Brief summary

Comparative study on clinical efficacy and safety of levocetirizine and desloratadine as measured by the subject's satisfaction/dissatisfaction after one week of treatment

Interventions

DRUGLevocetirizine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Clinical history of SAR known and treated since 2 years. * Positive skin prick test (wheal \> 3 mm larger than the diluent control) or RAST (≥3.5 IU/ml) to grass pollen (less than 1 year). * Minimum mean T5SS of 8 during the baseline period.

Exclusion criteria

* Have an associated asthma requiring a daily treatment other than β2 short acting agonist prn * Have atopic dermatitis or urticaria requiring antihistamine treatment or the administration of oral or topical corticosteroids and any other disease requiring the administration of oral or topical corticosteroids

Design outcomes

Primary

Measure	Time frame
Subjects' satisfaction / dissatisfaction after the first week of treatment.	—

Secondary

Measure	Time frame
allergic rhinitis symptoms scores over the first week of treatment , subject's satisfaction / dissatisfaction of their choice of treatment after the first week of treatment, time to first feeling of (sufficient) symptom improvement during the first we	—

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026