Comparison of Eprosartan/HCT Versus Enalapril/HCT in Hypertensives With Type II Diabetes

A Multi-Center, Double-Blind, Randomized Study Comparing the Efficacy of Combination Therapy of Eprosartan Respectively Ramipril With Low-Dose Hydrochlorothiazide and Moxonidine on Blood Pressure Levels in Patients With Hypertension and Associated Diabetes Mellitus Type 2

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00160160

Enrollment

440

Registered

2005-09-12

Start date

2004-10-31

Completion date

Unknown

Last updated

2009-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension, Type 2 Diabetes

Keywords

comparator trial, hypertension, diabetes, blood pressure

Brief summary

This study is to demonstrate the superiority of combination of eprosartan/HCTZ versus ramipril/HCTZ.

Interventions

DRUGeprosartan/HCTZ

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

40 Years to 80 Years

Healthy volunteers

Inclusion criteria

* essential hypertension, * diabetes type 2

Exclusion criteria

* severe cardiovascular disease, * grade 3 hypertension, * secondary hypertension, * abnormal liver enzymes

Design outcomes

Primary

Measure	Time frame
Blood pressure reduction	—

Secondary

Measure	Time frame
Comparison of responder rates	—

Countries

Canada, Denmark, France, Germany, Italy, Norway, Spain, Sweden, United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026