Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With CHF and Renal Impairment

Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With Congestive Heart Failure (CHF) and Renal Impairment

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00159614

Enrollment

Registered

2005-09-12

Start date

2005-09-30

Completion date

Unknown

Last updated

2008-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure, Congestive, Renal Insufficiency

Keywords

renal insufficiency, diuretic, heart failure, congestive

Brief summary

The purpose of this study is to characterize the safety and tolerability of KW-3902IV and measure its effect on renal function.

Interventions

DRUGKW-3902IV

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Stable congestive heart failure * Impaired renal function * Taking oral loop diuretic

Exclusion criteria

* Acutely decompensated (unstable) and end stage heart failure * Diuretics other than loop diuretics * Pregnant or nursing * Inability to follow instructions * Participation in another clinical trial within past 30 days

Design outcomes

Primary

Measure	Time frame
Comparison of KW-3902IV alone or with loop diuretic on renal function.	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026