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A Clinical Pathway for Nursing Home Acquired Pneumonia

A Randomized Control Trial of a Clinical Pathway for Nursing Home Pneumonia.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00157612
Enrollment
680
Registered
2005-09-12
Start date
2001-01-31
Completion date
2005-07-31
Last updated
2018-10-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower Respiratory Tract Infection, Pneumonia

Keywords

pneumonia, lower respiratory tract infection, clinical pathway, nursing home, long-term care, randomized control trial

Brief summary

Nursing home residents are frequently transferred to hospital for management of pneumonia. This often leads to hospital related complications and is a burden on the acute care health system. The purpose of this study is to assess whether managing residents with pneumonia and lower respiratory tract infection on site in the nursing home can reduce hospital admissions and can reduce complications and improve quality of life for residents. We have randomized residents with nursing home acquired pneumonia to on-site management, using a clinical pathway, versus usual care.

Detailed description

We conducted a cluster-randomized controlled trial where nursing homes were randomized to either use of a clinical pathway or usual care for management of nursing home acquired pneumonia. The clinical pathway included chest radiographs performed on-site in the nursing home by a mobile x-ray unit, use of hypodermocylysis (subcutaneous infusion) for re-hydration, administration of an oral antimicrobials, and use of pulse oximetry to assess oxygenation. The main outcomes were hospital admission rate and length of stay. Secondary outcomes included health related quality of life, rates of both infectious and non-infectious complications within four weeks of onset of symptoms; mortality rate of residents with pneumonia (death from all causes within 30 days of onset of symptoms. Time to stabilization of vital signs, as well as functional status at four weeks, were assessed.

Interventions

PROCEDUREa clinical pathway nursing home acquired pneumonia

treatment in nursing homes according to a clinical pathway, which included use of oral anti-microbials, portable chest radiographs, oxygen saturation monitoring, rehydrations and close monitoring by research nurse

Sponsors

Canadian Institutes of Health Research (CIHR)
CollaboratorOTHER_GOV
McMaster University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
64 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Symptoms or signs of lower respiratory tract infection as defined by standardized criteria.

Exclusion criteria

* Residents were excluded if they were not expected to live longer than 30 days from the date of enrollment, had a previous anaphylactic or serious allergic reaction to quinolones, had advanced directives that they are not be transferred to hospital for treatment.

Design outcomes

Primary

MeasureTime frame
Hospital admission, length of stay

Secondary

MeasureTime frame
Health related quality of life,
complication rates,
mortality,
functional status,
time to stabilization of vital signs

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 11, 2026