Respiration, Artificial
Conditions
Brief summary
Protocol directed weaning has been shown to reduce the duration of mechanical ventilation for patients admitted to the intensive care unit (ICU) of tertiary centres. However, this benefit has not previously been studied in a community hospital setting. We therefore sought to evaluate the impact of an evidence-based weaning guideline on the outcomes for patients receiving mechanical ventilation in the ICUs of community hospitals in a cluster randomized controlled trial involving 11 community hospitals.
Interventions
PROCEDUREEvidence based weaning protocol
Sponsors
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients ventilated for more than 24 hours
Exclusion criteria
* patients less than 16 years of age patients who receive only non-invasive ventilation patients chronically ventilated at time of ICU admission patients who will not be candidates for weaning from ventilation at time of admission If withdrawl of life support is imminent at the point the patient has been ventilated for 24 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICU length of stay | — |
Secondary
| Measure | Time frame |
|---|---|
| length of hospital stay | — |
| complications (re-intubation within 48 hours, pneumonia within 48 hours) | — |
| ICU mortality | — |
| duration of ventilation | — |
| ICU readmissions | — |
| Qulaity of life | — |
| Hospital mortality | — |
Countries
Canada
Outcome results
None listed