Kidney Diseases, Sleep Disorders
Conditions
Keywords
sleep disorder, peritoneal dialysis, cognitive-behavioral therapy, sleep disorder:C23.888.592.796, peritoneal dialysis: F03.870.664
Brief summary
Sleep disturbance is prevalent in chronic dialysis patients and there is a negative correlation between the quality of life and overall survival and sleep disturbance in them. Cognitive-behavioral therapy is an effective behavioral therapy for insomnia clinically. In previous studies, cognitive-behavioral therapy can redress anxiety in chronic hemodialysis patients. This study tries to elucidate its therapeutic effect on the sleep disturbance in chronic peritoneal dialysis patients.
Detailed description
Sleep disturbance is prevalent in chronic dialysis patients and there is a negative correlation between the quality of life and overall survival and sleep disturbance in them. So many factors interfering the sleep of these patients, however, there is no effective therapy for them except some drugs, such as hypnotics or anxiolytics. Cognitive-behavioral therapy is an effective behavioral therapy for insomnia clinically and it contains three therapeutic domains including stimulus control, sleep restriction therapy, and relaxation training. It has been proven to be beneficial in improving sleep pattern in chronic insomnia and cancer patients and alcoholism. In previous studies, cognitive-behavioral therapy can redress anxiety in chronic hemodialysis patients, however, there is no clinical evidence revealing its effectiveness upon sleep disorders in hemodialysis and peritoneal dialysis patients. Our study tries to elucidate the therapeutic effect of cognitive-behavioral therapy on the sleep disturbance in chronic peritoneal dialysis patients. We will perform cognitive-behavioral therapy to eligible peritoneal dialysis patients and evaluate the sleep condition before and after the therapy. Moreover, clinical conditions, biochemical and hematological parameters, inflammatory mediators in blood will be measured at baseline, before and after therapy.
Interventions
BEHAVIORALcognitive-behavioral therapy
Sponsors
Far Eastern Memorial Hospital
National Taiwan University Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Undergoing peritoneal dialysis (PD) for at least 3 months * Older than 18 years * Have sleep disturbance subjectively
Exclusion criteria
* Unstable clinical conditions or evidence of malignancy * Pregnancy * Participation in another study that would interfere with the outcome of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Check Pittsburgh Sleep Quality Index and restless leg syndrome index: in 1st and 3rd months | — |
Secondary
| Measure | Time frame |
|---|---|
| The hematologic, biochemical markers, and peritoneal function in 1st and 3rd months | — |
Countries
Taiwan
Contacts
Primary ContactTun-Jun Tsai, Ph.D., M.D
Outcome results
None listed