Comparison of Vascular Effects After Therapy With Irbesartan and Atorvastatin.

Characterization of Local Vascular Effects of Angiotensin II and Histamine After Treatment With Irbesartan and Atorvastatin.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00154024

Enrollment

Unknown

Registered

2005-09-12

Start date

2003-03-31

Completion date

2006-10-31

Last updated

2006-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Subjects

Keywords

venoconstriction, venodilation, pleiotropic effects

Brief summary

Vascular responses to angiotensin II and histamine are compared before and after 30 days of systemic treatment with either irbesartan 150 mg or atorvastatin 20 mg.

Detailed description

Vascular responses to angiotensin II and histamine are compared before and after 30 days of systemic treatment with either irbesartan 150 mg or atorvastatin 20 mg.

Interventions

DRUGatorvastatin

DRUGirbesartan

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

MALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy subjects * no relevant disease * amendment: hypercholesterolaemic subjects

Exclusion criteria

* any relevant disease

Design outcomes

Primary

Measure	Time frame
vascular responses after treatment.	—

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 7, 2026