Skip to content

A Clinic-based Prevention Program for Families of Depressed Mothers

A Clinic-based Program for Families of Depressed Mothers

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00149812
Enrollment
26
Registered
2005-09-08
Start date
2005-01-31
Completion date
2008-12-31
Last updated
2016-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Depression

Keywords

Depression, Child disruptive behavior, Family functioning

Brief summary

This study will assess the effectiveness of the Keeping Families Strong program (KFS) in avoiding or delaying the onset of psychiatric disorders among children with depressed mothers.

Detailed description

Children of depressed mothers are at high risk for developing serious psychiatric disorders. While genetics can account for about 34% of cases of childhood psychiatric disorders, children of depressed parents are at an even greater risk of developing mental disorders. The Keeping Families Strong program, or KFS, was built from evidence-based prevention programs. Its goal is to provide educational, cognitive, and behavioral interventions. These interventions are meant to enhance understanding about depression and its effects on families, improve communication within families, enhance social support, increase positive and consistent parenting, and improve child coping. This will likely improve the children's mental health, as well as positively affect the short- and long-term outcomes of parents recovering from a depressive episode. This study will evaluate the effectiveness of the KFS program in avoiding or delaying the onset of psychiatric disorders among children with depressed mothers. This 10-week, open-label program will involve 12 meetings, lasting 2 hours each. The parents and the children will attend separate meetings each week on the same nights. Children are prone to take on their parents' responsibilities to prevent them from becoming depressed. In order to avoid this, the children's meetings will focus on clarifying role responsibilities. There will be two additional follow-up meetings in the 3 months following completion of the program. All caregivers are encouraged to participate, including depressed fathers.

Interventions

BEHAVIORALFamily Functioning Intervention

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
Johns Hopkins Bloomberg School of Public Health
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
8 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Parent in treatment for depression * Parent in maintenance phase of treatment

Exclusion criteria

* Active substance abuse * Substantial cognitive impairment * Psychosis

Design outcomes

Primary

MeasureTime frame
Acceptability of program to parents, children, clinicians, and administrators throughout 10 weeks10 weeks

Secondary

MeasureTime frame
Improvement in the understanding of depression, family communication, parenting practices, and child coping over a one-year period1 year

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026