Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00144950

Enrollment

Registered

2005-09-05

Start date

Unknown

Completion date

Unknown

Last updated

2005-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Empyema

Brief summary

This study will compare VATS versus chest drain insertion and urokinase in the treatment of childhood empema by a randomised prospective study.

Interventions

DRUGinsertion of a chest drain with urokinase instillation

PROCEDUREprimary video-assisted thorascopic surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

0 Years to 16 Years

Healthy volunteers

Inclusion criteria

* patients under the age of 16 referred to GOSH for management of empyema

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
length of hospital stay	—

Secondary

Measure	Time frame
radiological changes at follow up	—

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 5, 2026