The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients

The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients: Barotrauma and Volutrauma

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00143468

Enrollment

100

Registered

2005-09-02

Start date

2005-03-31

Completion date

2008-05-31

Last updated

2011-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Lung Injury, ARDS

Keywords

gas exchange, respiratory mechanics

Brief summary

The investigators aim to study the specific elastance in ALI/ARDS patients during invasive mechanical ventilation.

Detailed description

In sedated and paralyzed ALI/ARDS patients, we studied the specific elastance and also, we compared the specific elastance to healthy subjects during invasive mechanical ventilation.

Interventions

BEHAVIORALmechanical ventilation

measurement of specific lung elastance during mechanical ventilation

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

16 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* Stable ALI/ARDS patients during invasive mechanical ventilation

Exclusion criteria

* Hemodynamic failure, pneumothorax

Design outcomes

Primary

Measure	Time frame
Specific elastance	5 minutes

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026