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Bone Status and Insulin Resistance in Hirsutism

Body Composition, Insulin Concentration, Androgens and Bone Status in Women Referred With Hirsutism

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00143052
Enrollment
50
Registered
2005-09-02
Start date
2002-01-31
Completion date
2007-01-31
Last updated
2008-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hirsutism

Keywords

Hirsutism, Bone status, Androgens, insulin

Brief summary

The purpose of this study is to investigate how the bones of hirsute women are different from bones of healthy women. The change in hormone content in the blood will also be investigated. The study can be used to evaluate whether it will be relevant to bone scan all newly referred hirsute women. Hirsute women are often over-weight and often have an increased amount of the male sex hormone in their blood. Their blood tests often show changes reminding of the ones seen in diabetic patients. All hirsute women referred to the department will undergo an investigation revealing the reason for the increased hair growth. The investigation includes clinical investigation (height, weight and degree of hair growth), blood tests (for hormone status and bone status analysis) and bone scanning of the abdomen (body composition). The trial includes a group of 50 strongly hairy women and a control group of 50 healthy women with normal hair growth. They are matched by body weight, since weight has great importance for the bone mineral content and thereby for osteoporosis in the long run.

Interventions

None listed

Sponsors

Odense University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 46 Years
Healthy volunteers
Yes

Inclusion criteria

Hirsute subjects: * Belonging to group 1 or 2. * Age: 20-46 * Hirsute score: \>7 * Written informed consent Control group: * Age: 20-46 * Hirsute score: 0 (without razing) * Regular menses * Written informed consent

Exclusion criteria

* Previous cosmetic treatment for hirsutism. * Use of contraceptive pill (within the past 6 months) * Systemic steroid treatment \> 6 weeks (ever) * Age above 46 years/post menopause (increased FSH) * Recognized diabetes mellitus or other endocrine disease * Eating disorder * Serious, treatment demanding disease

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026