The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients

Comparison Between Two Different Proportions of Omega-3- and Omega-6-Fatty Acids in the Parenteral Nutrition of Critically Ill Patients

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00142220

Enrollment

160

Registered

2005-09-02

Start date

2004-01-31

Completion date

Unknown

Last updated

2006-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis Syndrome

Brief summary

We study whether an increased proportion of omega-3-fatty acids (contained in fish oil) in the nutrition of critically ill patients reduces systemic inflammation.

Interventions

DRUGDefined percentage of omega-3-fatty acids

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

0 Years to No maximum

Healthy volunteers

Inclusion criteria

* indication for parenteral nutrition

Exclusion criteria

* hypertriglyceridemia * coagulation disorder * decompensated liver cirrhosis or acute liver failure

Design outcomes

Primary

Measure	Time frame
level of IL-6 in serum	—
HLA-expression on monocytes	—

Secondary

Measure	Time frame
duration of ICU stay	—
number of nosocomial infections	—
SOFA score	—
mortality	—
days on mechanical ventilation	—

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026