The Effect of Cycling Off Criteria During Pressure Support Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00141440

Enrollment

Registered

2005-09-01

Start date

2005-07-31

Completion date

2007-03-31

Last updated

2009-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

gas exchange, pressure support ventilation, respiratory mechanics, COPD patients

Brief summary

The investigators' aim is to study the effect of cycling off criteria during pressure support ventilation in COPD patients at two levels of PEEP and PSV.

Detailed description

In this study two levels of cycling off criteria at two levels of PEEP and PSV were tested in term of gas exchange, respiratory mechanics, work of breathing and patient comfort.

Interventions

PROCEDUREmechanical ventilation

evaluated the effect of two different cycling off criteria on breathing pattern, respiratory effort, and gas exchange in patients with chronic obstructive pulmonary disease

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

16 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Stable COPD patients during invasive mechanical ventilation

Exclusion criteria

* Hemodynamic instability, * Paralysis

Design outcomes

Primary

Measure	Time frame
Respiratory mechanics, gas exchange	2 minutes

Secondary

Measure	Time frame
Comfort of breathing	2 minutes

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026