Pregabalin In Partial Seizures: An Open-Label, International, Multicenter Add-On Therapy Trial.

Pregabalin In Partial Seizures (Preps) : An Open-Label, International, Multicenter Add-On Therapy Trial

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00141427

Enrollment

540

Registered

2005-09-01

Start date

2004-11-30

Completion date

2006-05-31

Last updated

2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seizures

Brief summary

To assess the clinical improvement (change in seizure frequency), safety and tolerability of patients with partial seizures following adjunctive therapy of pregabalin BID in addition to existing standard AEDs.

Interventions

DRUGPregabalin

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Male and female subjects with a diagnosis of partial epilepsy. * 18 years and older.

Exclusion criteria

* Having a treatable cause of seizure. * Having a progressive neurological or systemic disorder

Design outcomes

Primary

Measure	Time frame
Reduction in seizure frequency.	—

Countries

Belgium, Finland, France, Netherlands, Poland, Portugal, Switzerland, United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026