Evaluation Of A Novel Methodology In The Assessment Of Urethral Function Using SS-RBX.

Measurement Of Urethral Function In Women With Stress Urinary Incontinence - Evaluation Of The Sensitivity Of Urethral Reflectometry Compared To Urethral Pressure Profilometry, Using [S,S]-Reboxetine To Detect Pharmacological Augmentation Of Urethral Pressure.

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00141128

Enrollment

Registered

2005-09-01

Start date

2005-12-31

Completion date

2006-06-30

Last updated

2011-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary Incontinence, Stress

Brief summary

SS-RBX will be used to evaluate pharmacodynamic changes in urethral function using a novel methodology

Interventions

DRUGSS-RBX

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Female * Stress urinary incontinence

Exclusion criteria

* Bladder outflow obstruction * Neurological disease

Design outcomes

Primary

Measure	Time frame
To assess the utility of urethral reflectometry in the detection of pharmacologically induced pressure changes in the female urethra.	—

Secondary

Measure	Time frame
To assess the effect of [S,S]-Reboxetine on urethral function in women with SUI.	—

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026