Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee

Comparison of the Efficacy and Safety of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00139295

Enrollment

Unknown

Registered

2005-08-31

Start date

2004-10-31

Completion date

2007-09-30

Last updated

2014-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Knee

Keywords

musculoskeletal, osteoarthritis of the knee

Brief summary

This is a clinical study to investigate the safety and efficacy of hylastan in treating patients with symptomatic osteoarthritis (OA) of the knee.

Interventions

DEVICEHylastan

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

40 Years to No maximum

Healthy volunteers

Inclusion criteria

* Diagnosed with OA of the knee * Have tried but not been sufficiently helped by conservative treatment, such as weight reduction and pain medications

Exclusion criteria

* Prior or concomitant treatments that would impede measurement of safety and efficacy

Design outcomes

Primary

Measure	Time frame
pain relief	—

Countries

Canada, France, Germany, United Kingdom, United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026