Arrhythmia, Cardiomyopathy, Muscular Dystrophy
Conditions
Keywords
Cardiomyopathy, Arrhythmia, Muscular Dystrophy
Brief summary
We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders.
Interventions
PROCEDUREBlood draw (genetic testing)
Blood draw (genetic testing)
Sponsors
University of Chicago
Study design
Observational model
FAMILY_BASED
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.
Exclusion criteria
* Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of genetic causes of cardiomyopathy | unlimited |
Countries
United States
Contacts
Primary ContactLisa Dellefave, MS
Backup ContactElizabeth McNally, MD PhD
Outcome results
None listed