Skip to content

Cognitive Remediation in Supported Employment at Human Service Center (HSC)

Cognitive Remediation in Supported Employment at HSC

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00138021
Acronym
CT+SE
Enrollment
50
Registered
2005-08-30
Start date
2005-07-31
Completion date
2008-05-31
Last updated
2007-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Symptoms, Mental Disorders, Schizophrenia, Vocational Rehabilitation

Keywords

Serious mental illness, Supported Employment, Cognitive remediation, Cognitive impairments

Brief summary

This project seeks to evaluate the feasibility and effectiveness of combining cognitive remediation and Supported Employment Program (SEP) services to improve work outcomes in people with a serious mental illness who have been unable to benefit from vocational services (i.e., acquire or maintain a job). Cognitive remediation involves treating and improving cognitive impairments, such as memory (e.g., short-term and working memory), attention span, or problem solving skills. It is hypothesized that cognitive remediation will significantly improve peoples' employment outcomes in a supported employment program.

Detailed description

Ample evidence documents that supported employment is an effective strategy for improving the vocational outcomes of persons with schizophrenia and other severe mental illnesses. However, a significant amount of clients receiving supported employment services work little or not at all. With respect to factors that may influence the work outcomes of persons participating in supported employment programs, cognitive functioning appears to be potentially important. Cognitive impairment in persons with severe mental illness (SMI) is strongly correlated with functional adjustment in the community and has been shown to be correlated with work, both contemporaneously and prospectively. Studies have demonstrated that clients who did not receive the full benefits of supported employment had more deficits in executive functioning, memory, and psychomotor speed than those clients who had better work outcomes. The current study will use a computerized cognitive training program that will be administered by a cognitive trainer. The program consists of 24 training modules (each one takes about one hour to complete). Clients in an SEP who have been unable to maintain a job that they acquired while in the program can participate in the research. Clients who have agreed to participate in the research project will be randomly assigned to either receive the computerized training and supported employment services (CT-SES) or supported employment services (SES) without the training (i.e., treatment-as-usual-condition). Both research groups will receive the same baseline, three-month, and 12-month follow up interviews that will consists of a brief clinical and neuropsychological evaluation, an assessment of problems associated with finding or maintaining employment, and employment outcomes while enrolled in the study. In addition, both groups will receive a telephonic interview at 18 and 24 months to assess their employment outcomes (clinical and neurological information will not be collected at 18 or 24 months).

Interventions

The cognitive training model used in the McGurk et al. (2005) study is referred to as the Thinking Skills for Work program. The program is a manualized, remediative and compensatory training intervention that is integrated with SE services. The program includes a cognitive trainer, a structured training manual (McGurk & Mueser, unpublished training manual) and a computer-based cognitive training program (described below).

Sponsors

Human Service Center, Illinois
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Enrolled in a Supported Employment Program * Has acquired and lost at least one job while in the Supported Employment Program * Presently unemployed

Exclusion criteria

* Has not acquired at least one job while in the Supported Employment Program * Presently employed

Design outcomes

Primary

MeasureTime frame
competitive employment status at 12, 18, and 24 months12, 18, and 24 months
number of days employed in a competitive job at 12, 18, and 24 monthsat 12, 18, and 24 months
number of jobs acquired and lost at 12, 18, and 24 monthsat 12, 18, and 24 months

Secondary

MeasureTime frame
clinical status at 3, 12, 18, and 24 months3, 12, 18, and 24 months
improvement in cognitive functioning (various measures of cognitive functioning) at 3, 12, 18, and 24 months3, 12, 18, and 24 months
retention in either research condition3 & 12 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026