Tubal Pregnancy
Conditions
Keywords
Ectopic pregnancy, Surgical treatment, Medical treatment, Fertility
Brief summary
Three protocols are used to treat ectopic pregnancies: medical treatment by methotrexate, conservative surgery or radical surgery. There are no data about subsequent fertility except in a cohort study. The investigators propose to evaluate the true subsequent fertility with a follow-up of 2 years, in a randomized controlled trial.
Detailed description
The first group includes non active ectopic pregnancies defined by score or algorithm. In this case, we propose a randomized controlled trial between medical and conservative surgery. In all others clinical situations, we proposed surgery treatment. In a randomized controlled trial we compare conservative versus radical treatment. The patients are followed-up during 2 years with phone contact every 6 months.
Interventions
PROCEDURETreatment of ectopic pregnancy
Sponsors
Hopital Antoine Beclere
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 44 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis by ultra sound of ectopic pregnancy (EP) * Patients aged \> 18 years old * Desire of future pregnancy
Exclusion criteria
* EP by failure of contraception * EP associated with in vitro fertilization (IVF)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subsequent fertility with 2 years follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications of treatments | — |
| Time of hospitalisation | — |
| Decrease curve of beta-hCG after treatment | — |
| Success rate in each group | — |
Countries
France
Contacts
Primary ContactFernandez Hervé, PhD MD
Outcome results
None listed