Tonsillitis
Conditions
Keywords
recurrent tonsillitis, streptococcus, tonsillectomy, prevention
Brief summary
The purpose of this study is to determine whether tonsillectomy is effective in preventing further streptococcal pharyngitis episodes in patients with recurrent tonsillitis.
Detailed description
Tonsillectomy is widely used worldwide in recurrent streptococcal tonsillitis, but its effect remains unknown. In this randomized controlled trial, the effect of tonsillectomy (compared to watchful waiting) in preventing further culture proven symptomatic streptococcal pharyngitis episodes is studied. In addition, symptoms after the operation, side effects, and life quality issues are recorded.
Interventions
PROCEDURE(adeno)tonsillectomy
Sponsors
Oulu University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
14 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* At least 3 tonsillitis episodes during the preceding year (at least one verified by culture or antigen testing)
Exclusion criteria
* Other serious illness * Long term antibiotic treatment for other disease * Documented immunologic disorder * Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| microbiologically confirmed streptococcal pharyngitis episodes | — |
Secondary
| Measure | Time frame |
|---|---|
| side effects | — |
| symptoms | — |
| quality of life issues | — |
Countries
Finland
Outcome results
None listed