Mechanical Ventilation
Conditions
Keywords
Proportional assisted ventilation, Pressure support ventilation, Synchronism during mechanical ventilation, Patients undergoing partial mechanical ventilation
Brief summary
Synchronism of gas flow delivered by the ventilator and muscular effort of the patient will be studied during two kinds of ventilation. The first one is the proportional assisted ventilation during which the gas flow is theoretically adapted to the patient's muscular effort within the breath. The second is the pressure support ventilation during which the gas flow is delivered to maintain the inspiratory pressure stable. The hypothesis is that the first mode allows a better synchronism.
Interventions
PROCEDUREMechanical ventilation
Sponsors
Hospices Civils de Lyon
Study design
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing partial ventilatory support
Exclusion criteria
* Patients failing the weaning process
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time lag between the onset of diaphragmatic electromyogram (EMG) signal and the zero crossing of the inspiratory flow, over five minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Number per minute of failing breaths: breath with muscular effort without any inspiratory flow | — |
Countries
France
Contacts
Primary ContactJean-Paul VIALE, MD, PhD
Outcome results
None listed