Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients With Headache and Dizziness or Epilepsy and Clinical Indication for an Angiography by Magnetic Imaging

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00132223

Enrollment

Registered

2005-08-19

Start date

2005-04-30

Completion date

2005-12-31

Last updated

2006-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Headache, Epilepsy, Dizziness

Keywords

magnetic imaging, angiography, contrast agent, signal/noise ratio, contrast/noise ratio, vessel

Brief summary

Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents. Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients. All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s. The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.

Interventions

DRUGContrast agent

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

SINGLE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Headache * Epilepsia * Dizziness

Exclusion criteria

* Pregnancy * Metal implants (e.g. pacemaker) * Contraindication for contrast agent * Multiple allergies

Design outcomes

Primary

Measure	Time frame
intensity of vessels, muscle, air	—

Secondary

Measure	Time frame
signal/noise ratio	—
contrast/nose ratio	—

Countries

Germany

Contacts

Primary ContactBoris Buerke, MD

buerkeb@uni-muenster.de00492518345123

Backup ContactBernd Tombach, MD

tombach@uni-muenster.de00492518345123

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026