Carotid Stenosis
Conditions
Keywords
Carotid artery stenosis, cost effectiveness, magnetic resonance angiography, computed tomography angiography, digital subtraction angiography
Brief summary
PURPOSE: The purpose of this clinical trial is to study the cost-effectiveness ratios of diagnostic strategies for the imaging assessment of symptomatic carotid stenosis. MATERIALS AND METHODS: The diagnostic accuracies of Doppler ultrasound (DUS), contrast-enhanced magnetic resonance angiography (CEMRA) and computed tomography angiography (CTA) were compared with digital subtraction angiography (DSA) in a multicenter study (CARMEDAS; 206 patients assessable) and in a meta-analysis (for CEMRA and CTA). The direct costs of each imaging method were calculated in 2 university medical centers. Eight hypothetical models were studied with DUS considered as the first-line imaging method and either CEMRA or CTA or DSA as the second or third line method. The effectiveness criterion was the number of potential avoided strokes for each strategy and for 1000 patients.
Interventions
PROCEDUREcontrast-enhanced magnetic resonance angiography
Sponsors
Hospices Civils de Lyon
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
Carotid artery stenosis \> 50%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the cost-effectiveness ratios of diagnostic strategies for the imaging assessment of symptomatic carotid stenosis | — |
Countries
France
Outcome results
None listed