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Psychodynamic Therapy for Treating Panic Disorder

Randomized Controlled Trial of Psychodynamic Psychotherapy vs. Applied Relaxation for Panic Disorder

Status
Completed
Phases
Phase 2Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00128388
Enrollment
49
Registered
2005-08-09
Start date
2000-02-29
Completion date
2005-07-31
Last updated
2013-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Panic Disorder

Keywords

panic disorder,, psychodynamic psychotherapy,, efficacy trial

Brief summary

This study will determine the effectiveness of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training in treating adults with panic disorder.

Detailed description

This is a randomized controlled trial of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training, a less active form of treatment in other studies, for adults with primary Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) panic disorder. Forty nine patients who have signed written consent who have primary DSM-IV panic disorder have been entered into the study. Randomization has been stratified by presence of major depression and use of psychoactive, anti-panic medications. Medications, if present, have been held constant. All patients have received 24 sessions of either psychodynamic psychotherapy, or applied relaxation training for panic disorder. This study is currently closed for recruitment, although final follow-up assessments have yet to be completed.

Interventions

OTHERPFPP

Psychoanalytic Psychotherapy for panic disorder

OTHERART

Applied Relaxation Training

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
Weill Medical College of Cornell University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No

Inclusion criteria

* 18-55 years old * Primary DSM-IV panic disorder with or without agoraphobia * Severity 5/8 minimum on the Anxiety Disorders Interview Schedule

Exclusion criteria

* Psychosis * Unstable medication dosage * Unwilling to discontinue ongoing psychotherapy * Organic mental syndrome * Substance use or abuse

Design outcomes

Primary

MeasureTime frame
PDSS (panic disorder severity scale)termination, 2, 4, 6, 12 month f/u

Secondary

MeasureTime frame
SDS (Sheehan disability scale)termination, 2, 4, 6, 12 month f/u
HARS (Hamilton anxiety rating scale)termination, 2, 4, 6, 12 month f/u
HDRS (Hamilton depression rating scale)termination, 2, 4, 6, 12 month f/u

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 7, 2026