Panic Disorder
Conditions
Keywords
panic disorder,, psychodynamic psychotherapy,, efficacy trial
Brief summary
This study will determine the effectiveness of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training in treating adults with panic disorder.
Detailed description
This is a randomized controlled trial of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training, a less active form of treatment in other studies, for adults with primary Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) panic disorder. Forty nine patients who have signed written consent who have primary DSM-IV panic disorder have been entered into the study. Randomization has been stratified by presence of major depression and use of psychoactive, anti-panic medications. Medications, if present, have been held constant. All patients have received 24 sessions of either psychodynamic psychotherapy, or applied relaxation training for panic disorder. This study is currently closed for recruitment, although final follow-up assessments have yet to be completed.
Interventions
Psychoanalytic Psychotherapy for panic disorder
Applied Relaxation Training
Sponsors
Study design
Eligibility
Inclusion criteria
* 18-55 years old * Primary DSM-IV panic disorder with or without agoraphobia * Severity 5/8 minimum on the Anxiety Disorders Interview Schedule
Exclusion criteria
* Psychosis * Unstable medication dosage * Unwilling to discontinue ongoing psychotherapy * Organic mental syndrome * Substance use or abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PDSS (panic disorder severity scale) | termination, 2, 4, 6, 12 month f/u |
Secondary
| Measure | Time frame |
|---|---|
| SDS (Sheehan disability scale) | termination, 2, 4, 6, 12 month f/u |
| HARS (Hamilton anxiety rating scale) | termination, 2, 4, 6, 12 month f/u |
| HDRS (Hamilton depression rating scale) | termination, 2, 4, 6, 12 month f/u |
Countries
United States