Obesity, Type 2 Diabetes Mellitus
Conditions
Keywords
Weight, Diet, exercise, maintenance
Brief summary
The purpose of this trial is to determine the most cost effective programme for overweight and obese individuals to maintain weight loss over a 2 year period.
Detailed description
Although short term weight loss is often achievable in overweight individuals, long term maintenance is generally poor. The researchers urgently need new information regarding the most cost effective programme(s) for maintenance of weight loss. This study will recruit 200 women and compare two approaches for providing support: one with intensive health professional support, the other peer group support facilitated by a research nurse with frequent 'weigh- ins'. The researchers will also compare two different diets one a high carbohydrate, high fibre, low glycaemic index diet versus one relatively high in monounsaturated fat and protein and low in glycaemic load.
Interventions
BEHAVIORALLifestyle: diet and exercise intervention
Sponsors
Edgar National Centre for Diabetes Research
University of Otago
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Female participants * Aged 25 to 70 * Those who have intentionally lost more than or equal to 5% of initial body weight in the previous 6 months will be recruited * Objective evidence that volunteers were overweight or obese and have lost weight will be obtained from doctors records
Exclusion criteria
* Presence of major illness including cancers * Established cardiovascular disease or stroke * Diabetes * Gestational diabetes * Renal disease * Malabsorption disorders * Thyroid disorders * Major psychiatric disorders * Taking weight loss medication or medications known to cause weight gain * Planning a pregnancy in the next 2 years * Those who do not intend to be in the area for the next 2 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Waist circumference and blood pressure | 2 years |
| Lipid profile and glucose and insulin | 2 years |
| Body composition | 2 years |
| Physical fitness | 2 years |
| Change in mood state | 2 years |
| Dietary intake | 2 years |
Countries
New Zealand
Outcome results
None listed