Cardiovascular Diseases, Hypertension, Sleep Apnea
Conditions
Brief summary
The objective of the study is to evaluate the effect of CPAP over the incidence of cardiovascular events and diagnosis of arterial hypertension in patients with sleep apnea. The hypothesis of the study is the following: The existence of sleep disordered breathing in the general population is associated to an increased incidence of arterial hypertension and to an increased risk of suffering cardiovascular disease. CPAP corrects respiratory disorders during sleep. Treatment with CPAP in subjects with sleep disordered breathing without daytime sleepiness reduces the incidence of systemic arterial hypertension and cardiovascular complications. The end points of the study are new diagnosis of arterial hypertension and new cardiovascular events. All patients, after randomization, will be followed for three years.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* Epworth \<10 * Apnea-Hypopnea Index ≥20
Exclusion criteria
* Presence of any chronic disease * Presence of cardiovascular disease * Refusal to sign informed consent * Drug addiction and/or alcoholism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypertension | — |
| Incidence of cardiovascular events | — |
Secondary
| Measure | Time frame |
|---|---|
| Relationship between hypertension and sleep apnea/hypopnea syndrome (SAHS) severity | — |
| Relationship between cardiovascular events and SAHS severity | — |
Countries
Spain