Reduction of Topical Anesthetic Time for Subcutaneous Port Access Using Ultrasound

Randomized Crossover Trial of Sonication Followed by 5 Minute LMX4 Application Compared With 30 Minute LMX4 Application for Topical Anesthesia Prior to Subcutaneous Port Access in Children

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00126919

Enrollment

Registered

2005-08-05

Start date

2004-10-31

Completion date

2006-10-31

Last updated

2012-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Brief summary

Children ages 3-17 who are undergoing port access receive both standard care, topical medicine for numbing (LMX4), and the study intervention which utilizes ultrasound to speed the onset of LMX4 from 30 minutes to 5 minutes. The procedures will be performed on 2 separate visits to the clinic. The child's pain with the access procedure is evaluated.

Interventions

DEVICESonoPrep

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

3 Years to 17 Years

Healthy volunteers

Inclusion criteria

* Children ages 3-17 with subcutaneous port

Exclusion criteria

* Emergent need for port access * Allergy to lidocaine sodium lauryl sulfate

Design outcomes

Primary

Measure	Time frame
pain	—

Secondary

Measure	Time frame
tolerability	—
safety-skin effects	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026