Biliary Tract Disease
Conditions
Keywords
a fatty meal, ERCP
Brief summary
This study is to determine if a fatty meal would improve the ERCP procedure.
Detailed description
A fatty meal is a potent stimulator of cholecystikinin (CCK) in human body. The biological effect of CCK is increasing bile secretion and relaxing the sphincter of Oddi. Theoretically, a fatty meal should facilitate the effect on cannulation at ERCP. If a fatty meal can make the major papilla cannulation easier, it may significantly shorten the procedure time for ERCP and even decrease complications of the procedure, since the complication rate of post-ERCP is positively related to the time of the procedure. Comparison: Approximately one hour before ERCP procedure, patient will have a fatty meal in the study group and normal saline in control group.
Interventions
BEHAVIORALa fatty meal
Approximately one hour before ERCP procedure, patient will have a fatty meal in the study group and normal saline in control group
Sponsors
Emory University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
TRIPLE (Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients, 18 years and older, who are scheduled for ERCP at Emory University Hospital and signed consent before the procedure.
Exclusion criteria
* Patients with a known allergy to milk or those who choose not to sign the consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a fatty meal in the study group and normal saline in control group | the procedure time for ERCP |
Secondary
| Measure | Time frame |
|---|---|
| follow up within 3 days for complication with relation to the cannulation time | within 3 days |
Countries
United States
Outcome results
None listed