Skip to content

Peripartum Bacteruria and Urinary Tract Infections (UTI)

Risk Factors for Postpartum Bacteruria, Does Labor Cause UTI?

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00121797
Enrollment
1000
Registered
2005-07-21
Start date
2004-01-31
Completion date
2005-06-30
Last updated
2006-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary Tract Infection

Keywords

Postpartum Period

Brief summary

In the last years urinary tract infections (UTI) and pyelonephritis have been the most common reason for readmission to our hospital after birth. UTI is know to be one of the leading causes of postpartum fever affecting about 3%-8% of all postpartum women. The investigators hypothesize that collecting urine cultures pre- and postnatally may help identify women at risk for developing UTI, while treating women with positive cultures could decrease the rehospitalization rate due to postpartum fever. Collecting data during delivery may help identify women at risk for this complication.

Detailed description

The study is planned as a randomized controlled study with 500 women in each arm. The study group will have pre and post labor urine cultures taken, and the risk factors during delivery will be documented, while the control group will have no cultures taken, as the common practice prior to the study. Women with positive cultures will be contacted by telephone, and antibiotic treatment recommended according to bacteria sensitivity. All women will be contacted by telephone 1 month post partum and data regarding urinary tract symptoms and need for hospitalization, will be collected. The rehospitalization rate will be documented and compared between the two groups. The assumption is that routine urine culture to women in the peripartum period may reduce the UTI rate and hospitalization after delivery.

Interventions

PROCEDUREurine culture
DRUGantibiotics according to culture

Sponsors

Hadassah Medical Organization
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
Yes

Inclusion criteria

* Parturients planned for vaginal delivery

Exclusion criteria

* Parturients receiving antibiotic treatment during delivery or in the week before

Design outcomes

Primary

MeasureTime frame
Rate of rehospitalization for postpartum fever
Incidence of UTI in the early puerperium

Countries

Israel

Contacts

Primary ContactArik Tzukert, DMD
arik@hadassah.org.il00 972 2 6776095
Backup ContactHadas Lemberg, PhD
lhadas@hadassah.org.il00 972 2 6777572

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026