Study to Determine the Utility of Wound Vacuum Assisted Closure (VAC) Compared to Conventional Saline Dressing Changes

A Prospective Study to Determine the Utility of Vacuum Assisted Closure (VAC) Compared to Conventional Saline Dressing Changes With Regards to Lower Extremity Fasciotomy Wound Healing, Complications, Cost and Patient and Nursing Satisfaction

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00121537

Enrollment

Registered

2005-07-21

Start date

2005-07-31

Completion date

2006-10-31

Last updated

2015-10-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Compartment Syndromes, Wounds

Keywords

wounds-open

Brief summary

The purpose of this study is to look at the use of the wound vacuum assisted closure (VAC) versus standard wet to dry dressing in treating lower leg fasciotomies.

Interventions

PROCEDUREWound Care - Wet to Dry Dressing Changes

DEVICEWound Care -Wound Vacuum Assisted Closure (VAC)

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

* four compartment fasciotomies performed on one or both lower extremities * subject and/or subject's legally authorized representative (next-of-kin) has voluntarily signed and dated informed consent.

Exclusion criteria

* inability to place wound VAC * contraindications for wound VAC use * pregnant females * prisoners

Design outcomes

Primary

Measure	Time frame
Rate of wound healing	—

Secondary

Measure	Time frame
Time to delayed primary wound closure	—
Time to completion of secondary healing	—
Patient satisfaction	—
Nurse satisfaction	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026