4% Intrauterine Lidocaine Infusion for Pain Management in First Trimester Abortions

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00121329

Enrollment

Registered

2005-07-21

Start date

Unknown

Completion date

2004-12-31

Last updated

2005-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

Pain with procedures

Brief summary

Recent studies have investigated the use of local anesthetics (i.e. lidocaine, mepivacaine) to lessen the pain experienced with minor gynecologic procedures such as endometrial biopsy and office hysteroscopy. Local anesthetic injected into the uterine cavity has been demonstrated effective in some studies at decreasing patient pain associated with these intrauterine procedures at an anesthetic concentration of at least 2%. Based on this evidence, we hypothesized that an intrauterine lidocaine infusion may reduce patient pain during first trimester abortions.

Interventions

DRUGIntrauterine lidocaine infusion 4%

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Age \> 18 years old * Good general health * English speaking * Confirmation of gestational age by ultrasound * Body weight \> 100 lbs. * Pregnancy \< 11 weeks

Design outcomes

Primary

Measure	Time frame
VAS scores during cervical dilation and uterine aspiration	—

Secondary

Measure	Time frame
Patient satisfaction, symptoms, lidocaine levels	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026