Evaluation of Acetabular Perfusion After Ganz Osteotomy by Positron Emission Tomography

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00119444

Enrollment

Registered

2005-07-13

Start date

2004-01-31

Completion date

2009-08-31

Last updated

2015-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Keywords

PET, Periacetabular osteotomy

Brief summary

The purpose of this study is to examine the blood flow in acetabulum after periacetabular osteotomy by Positron Emission Tomography (PET).

Detailed description

As a consequence of periacetabular osteotomy the blood flow in acetabulum is decreased. After periacetabular osteotomy has been performed there is fine contact between the osteotomised acetabulum and the rest of the pelvis and the potential for healing is good. However, it has not been investigated how much the blood flow in acetabulum is changed after surgery. The blood flow is considered to be vital for how the pelvis heals after surgery. Most likely, the blood flow is important in relation to which degree osteoarthritis can be prevented after periacetabular osteotomy. It is possible to estimate the blood flow by Positron Emission Tomography of the dysplastic hip joint pre- and postoperatively. In this study the blood flow and fluoride uptake is quantified by Positron emission tomography based on measurements of O-15 water and F-18 fluoride.

Interventions

PROCEDUREPeriacetabular osteotomy

osteotomy of the pelvis to increase acetabular coverage

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Patients with radiologically diagnosed hip dysplasia (CE-angle \< 25°). * Patients with osteoarthritis graded 0, 1 or 2 defined according to Tönnis' classification. Patients with pain from hip * Age \> 18 years. * Minimum 110° flexion in hip joint and closed growth zones in the pelvic. * Informed consent.

Exclusion criteria

* Patients with neurological diseases * Patients with calvé-Legg-Perthes syndrome. * Patients where an femoral intertrochanteric osteotomy is necessary. * Patients with medical sequelae after earlier hip surgery. * Females who are pregnant. * Patients with metal implants.

Design outcomes

Primary

Measure	Time frame
changes in blood flow	within the first three weeks after operation

Secondary

Measure	Time frame
fluoride uptake	within the first three weeks after operation

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026