Alcohol Abuse, Cannabis Abuse, Major Depressive Disorder, Substance-Related Disorders
Conditions
Keywords
Alcohol Abuse/Dependence, Alcohol Use Disorders, Cannabis Abuse/Dependence, Depression, Dual diagnosis, Dysthymia, Stimulant Abuse/Dependence, Substance Use Disorders
Brief summary
The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use disorders.
Detailed description
Depression is the most frequent co-occuring mental health disorder among adults with substance use disorders, and such comorbidity is often associated with poorer treatment outcomes. Although there is an urgent need for effective treatments specific for dual-diagnosis adults, few studies have been conducted to address this need. Comparison: This study will compare substance use and depression symptoms of individuals in two different psychotherapy groups: Integrated Cognitive Behavioral Therapy and Twelve Step Facilitation Therapy. Symptoms and substance use will be compared during the active treatment phase (24 weeks) and for one year following the end of the active treatment.
Interventions
BEHAVIORALIntegrated Cognitive Behavioral Therapy
BEHAVIORALTwelve Step Facilitation Therapy
Sponsors
US Department of Veterans Affairs
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Individuals diagnosed with one or more substance use disorders (alcohol, cannabis, and or stimulant abuse/dependence) and an independent co-occurring depressive disorder (major depression or dysthymia) will be included.
Exclusion criteria
* Individuals with substance induced mood disorders and individuals experiencing persistent psychotic symptoms. * Those with life threatening or unstable medical illness, neurological disorders, or inability to read will be excluded. * Individuals currently prescribed steroids, disulfiram, or long acting benzodiazepines will be excluded.
Countries
United States
Outcome results
None listed