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Patient Centered Communication Training to Reduce Antibiotic Use in Acute Respiratory Tract Infections

Multidimensional Intervention Program to Reduce Antibiotic Prescriptions for Acute Respiratory Tract Infections in Adults: a Randomized Controlled Trial in Primary Care

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00105248
Enrollment
900
Registered
2005-03-11
Start date
2004-01-31
Completion date
2004-06-30
Last updated
2016-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Tract Infections

Keywords

acute repiratory infections, antibiotic therapy, patient-centred communication, randomized controlled trial

Brief summary

The purpose of this study is to evaluate the effectiveness of a short training program for general practitioners in patient-centered communication to reduce antibiotic prescription for acute respiratory tract infections (ARTI).

Detailed description

Acute respiratory tract infections (ARTI) constitute the most frequent reason for seeking ambulatory care and for the prescription of antibiotics, despite the mostly viral origin of ARTI. Antibiotic prescriptions for ARTI increase unnecessary drug expenditures and are the main reason for increasing drug resistance of common bacteria. Evidence from intervention studies shows that merely providing physicians with guidelines and educational material for the management of acute respiratory tract infections is not enough to reduce antibiotic prescriptions for these conditions. The main reasons for antibiotic prescription in ARTI are non-medical and related to the physician patient relationship, patients' expectations and beliefs about the benefit of antibiotics. Therefore patient-centered communication could be a promising approach to reduce the rate of antibiotic prescription in ambulatory care. Comparison: General practitioners (GPs) trained in patient-centered communication in addition to evidence-based guidelines for diagnosis and treatment of ARTI compared to GPs just introduced to evidence-based guidelines.

Interventions

BEHAVIORALpatient-centered communication training

Sponsors

Basel Institute of Clinical Epidemiology (BICE)
CollaboratorOTHER
Swiss National Science Foundation
CollaboratorOTHER
Novartis
CollaboratorINDUSTRY
University Hospital, Basel, Switzerland
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
SINGLE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 years or older * Symptoms of an acute respiratory tract infection for \>1 and \<28 days

Exclusion criteria

* Patients without informed consent * Not fluent in German * Patients with a psychiatric disorder * Patients with a recurrent respiratory system infection with antibiotic treatment in the previous 4 weeks

Design outcomes

Primary

MeasureTime frame
Up-take of antibiotic prescription confirmed by pharmacists within 2 weeks following the initial consultation

Secondary

MeasureTime frame
patient enablement (on validated scale)
days with restriction from ARTI within 14 days initial consultation
Patient satisfaction with consultation (on validated scale)
re-consultation rates
days off from work
side effects from medication

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026