Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1

Cocaine Relapse Prevention II

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00094315

Enrollment

Registered

2004-10-15

Start date

2004-09-30

Completion date

2005-07-31

Last updated

2017-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine-Related Disorders

Brief summary

To study of classical conditioning mechanisms associated with arousal, craving and cocaine use.

Detailed description

This is a single-site, double-blind, placebo-controlled crossover study of classical conditioning mechanisms associated with arousal, craving and cocaine use.

Interventions

DRUGCocaine (IV)

Eligibility

Sex/Gender

ALL

Age

18 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

* Be English-speaking volunteers who are cocaine dependent * Be non-treatment seeking at the time of the study * Meet DSM-IV criteria for cocaine dependence * Have ECG showing normal sinus rhythm, normal conductivity, and non clinically significant arrhythmias * Females must provide a negative pregnancy test and agree to use birth control * Have baseline laboratory tests within normal limits

Exclusion criteria

* Please contact site for more information

Design outcomes

Primary

Measure	Time frame
Stimulated and non-stimulated craving	—
Cocaine assessment	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026