Interactions Between Cocaine and Ethanol and Disulfiram - 1

Interactions Between IV Cocaine and Ethanol and Oral Disulfiram

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00094289

Enrollment

Registered

2004-10-15

Start date

2004-08-31

Completion date

2005-07-31

Last updated

2017-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol-Related Disorders, Cocaine-Related Disorders

Brief summary

The purpose of this study is to assess potential interactions between intravenous cocaine and ethanol and oral disulfiram.

Detailed description

This is a two-site, double blind, placebo-controlled inpatient study to determine the cardiovascular and psychiatric safety of alcohol use in cocaine-dependent subjects who had used cocaine after treatment with disulfiram.

Interventions

DRUGDisulfiram

Study design

Primary purpose

TREATMENT

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Must meet DSM-4 criteria for cocaine abuse or dependence and are not seeking treatment. * Ability to verbalize understanding of consent form and provide written informed consent and verbalize willingness to complete study procedures; be able to comply with protocol requirements.

Exclusion criteria

* Please contact site for more information.

Design outcomes

Primary

Measure	Time frame
Safety assessments	—
Psychological effects	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026