Treatment of Adolescent Suicide Attempters (TASA)

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00080158

Enrollment

120

Registered

2004-03-26

Start date

2004-03-31

Completion date

2007-06-30

Last updated

2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Suicide, Attempted

Keywords

Dysthymic Disorder, Adolescent

Brief summary

The purpose of this study is to compare the effects of three types of treatments for depressed teenagers who have attempted suicide.

Detailed description

Suicide is the third leading cause of death in adolescents and is a major public health problem. Depression is the most common diagnosis for adolescent suicide attempts. Little is known about what treatment is best for these adolescents since they are usually excluded from participation in research studies. Participants in this study will be randomly assigned to receive carefully monitored antidepressant medication with routine support and management, cognitive behavioral therapy (CBT), or a combination of antidepressant medication plus CBT.

Interventions

DRUGfluoxetine

DRUGsertraline

DRUGcitalopram

DRUGescitalopram

DRUGbupropion

DRUGmirtazapine

DRUGvenlafaxine

DRUGlithium

BEHAVIORALCognitive Behavioral Therapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

12 Years to 18 Years

Healthy volunteers

Inclusion criteria

* At least one suicide attempt or interrupted attempt within the past 45 days * Continuously reside with a primary caretaker (parent, legal guardian, foster parent) for at least 6 months that can provide legal consent

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026