The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00072917

Enrollment

100

Registered

2003-11-14

Start date

2003-10-31

Completion date

2008-06-30

Last updated

2010-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Thinness, Weight Gain

Keywords

obesity, thinness, weight gain, physical activity, diet, fat oxidation, hunger, feeding behavior, overfeeding

Brief summary

This is a longitudinal cohort study of how the responses to a 3 day period of controlled overfeeding relate to subsequent weight gain. We hypothesize that thin individuals are resistant to weight gain because they respond to periods of overfeeding by increasing fat oxidation, reducing food intake, and increasing physical activity relative to those who gain weight over time.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

25 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* Half of the subjects will be women, half will be men, * age 25-35, * a range of BMI's from 19-27, for the 'thin subjects' there should be no 1st degree relatives with a BMI\>30. * Subjects should not engage in planned physical activity more than 3 hrs per week. * For the obesity prone group there should be at least 1 1st degree relative with a BMI\>30.

Countries

United States

Outcome results