Treatment for Women With Post-Traumatic Stress Disorder Related to Childhood Abuse

Skills Training, Exposure, and Their Combination in Childhood Abuse PTSD

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00069381

Enrollment

144

Registered

2003-09-25

Start date

2002-04-30

Completion date

2009-07-31

Last updated

2013-03-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress Disorders, Post-Traumatic

Brief summary

This study will compare one- and two-component treatments in women with post-traumatic stress disorder (PTSD).

Detailed description

PTSD is a debilitating and often chronic anxiety disorder with serious psychiatric comorbidity. The most common trauma associated with PTSD among women is childhood abuse. PTSD related to childhood abuse may cause problems with emotion regulation and interpersonal functioning. This study will address three domains of PTSD related to childhood abuse: emotion management problems, interpersonal problems, and PTSD symptoms. Participants in this study will be randomly assigned to 16 sessions of one of three treatments: Skills Training for Affective and Interpersonal Regulation (STAIR), which focuses on helping individuals strengthen and build skills in managing feelings and improving interpersonal relationships; Modified Prolonged Exposure (MPE), which focuses on developing narratives of abuse history and completing an emotional processing of the trauma in a safe environment; and a combination of STAIR and MPE. Dropout rates and adverse effects will be measured.

Interventions

BEHAVIORALPsychotherapy treatment

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

22 Years to 65 Years

Healthy volunteers

Inclusion criteria

* DSM-IV criteria for Post-Traumatic Stress Disorder related to childhood physical and/or sexual abuse by a care-giver * At least one clear memory of the abuse * Willing to have all assessments tape recorded and sessions video taped * Willing to maintain any concurrent treatments for the duration of the study

Exclusion criteria

* Bipolar Disorder * Eating Disorder * Borderline Personality Disorder * Active substance abuse or dependence * Living with the abuser * Self mutilation * Pregnancy

Design outcomes

Primary

Measure	Time frame
outcome	within study timeframe

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026